Alloimmunization

Hemolytic disease of the fetus and newborn remains a significant public health concern with an estimated incidence of 1.6 per 1000 live births. When any fetal blood group factor inherited from the father is not possessed by the mother it may stimulate an immune reaction and the formation of maternal antibodies (alloimmunization) which may lead to transplacental passage and hemolytic disease in the fetus and neonate. Undiagnosed and untreated, alloimmunization can lead to significant perinatal morbidity and mortality. 1 CPD Point is Allocated